A stent is a tube-like device placed in arteries to avoid blockage and ensure proper blood flow. Stents have been crucial for avoiding complications in patients with myocardial infarction. There are three major types of stents currently approved in the global coronary and peripheral vascular stents market: bare metal stents (BMS), drug eluting stents (DES), and bioresorbable scaffold (BAS).
Bare metal stents act as scaffold to keep the artery open and maintains normal blood flow. New tissue which grows during the healing process helps the stent in place. Drug eluting stents are advanced stents coated with drugs that are slowly released into the blood stream to prevent inflammation and restenosis in the blood vessel. Restenosis is recurrence of abnormal narrowing of an artery and remains largely unpredictable occurring on 10% to 40% of the patients. Hence drug eluting stents have proved to be a better alternative to maintaining proper blood flow. Cypher (sirolimus), Ravel (sirolimus), Sirius (sirolimus), Elutes (paclitaxel), Aspect (paclitaxel) and Taxus (paclitaxel) were some of early brands introduced in the market. BMS and DES are generally made of cobalt-chromium or stainless steel. Advent of biodegradable technology brought new trend in the vascular stents market. Absorb bioresorbable scaffold introduced by Abbott was approved in July 2016 by the U.S. FDA is proven to completely dissolve in approximately 3 years after its implant.
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Peripheral artery stents are different from coronary stents in that they are more flexible. These stents are usually made of nitinol (nickel titanium alloy) which possesses characteristics of shape memory, and high elasticity. Vascuflex, Misago, Xpert, Everflex, Zilver are some of the key brands in peripheral vascular stents market.
According to the World Health organization (WHO), approximately 17 million people died due to cardiovascular diseases globally in 2012, which represents over 30% of all mortalities. Data also reviles that more than 75% of these mortalities occur in middle- and low-income countries. Russia, Romania, Bulgaria, Hungary and Argentina are the top five countries with highest rate of mortalities due to heart diseases. Hence there is a higher demand of low-cost stents in these geographies. Prevalence of peripheral vascular diseases is higher in western countries including the U.S., Canada, and major European countries.
Abbott; B. Braun Melsungen AG, Boston Scientific Corporation, Biotronik SE & Co. KG, C. R. Bard, Inc. and Cook Medical, Medtronic, , Stentys SA, and Terumo Corporation are some of the major players in the global coronary and peripheral vascular stents market.
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